Wait, what? 0 George Street? Only in Charleston do you find these charming, idiosyncratic addresses (keep your eyes peeled for others like 27 ½ State Street!). But don't be fooled by the numbers, this diminutive hotel is 100. Have your morning coffee in the lush courtyard or spring for room service in one of the 18 serene rooms in these restored 1804 buildings.

Seafood is the name of the game at this teeny tiny raw bar that does everything right, whether it be po' boys, ceviche or simply good ole oysters.